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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SPR
All Species:
22.42
Human Site:
S40
Identified Species:
37.95
UniProt:
P35270
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35270
NP_003115.1
261
28048
S40
P
G
S
V
L
V
L
S
A
R
N
D
E
A
L
Chimpanzee
Pan troglodytes
XP_525784
261
27897
S40
P
G
S
V
L
V
L
S
A
R
N
D
E
A
L
Rhesus Macaque
Macaca mulatta
XP_001103332
261
28016
N40
P
G
S
V
L
V
L
N
A
R
N
N
E
A
L
Dog
Lupus familis
XP_540234
267
28592
S46
P
G
S
V
L
V
L
S
A
R
N
I
E
A
L
Cat
Felis silvestris
Mouse
Mus musculus
Q64105
261
27865
S41
P
G
S
V
M
L
V
S
A
R
S
E
S
M
L
Rat
Rattus norvegicus
P18297
262
28110
S41
P
G
S
V
L
L
L
S
A
R
S
D
S
M
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520473
236
25629
E34
R
M
E
G
A
Y
A
E
G
P
G
S
V
L
D
Chicken
Gallus gallus
Q8JIS3
246
26149
T42
R
V
T
A
L
S
R
T
A
A
D
L
E
S
L
Frog
Xenopus laevis
Q7ZY31
263
28687
V44
P
G
S
T
L
L
L
V
S
R
T
E
E
A
L
Zebra Danio
Brachydanio rerio
NP_001019601
261
28523
A42
P
G
S
V
L
V
L
A
A
R
S
E
E
Q
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624245
354
39811
L133
K
G
S
H
I
L
L
L
A
T
N
L
N
A
L
Nematode Worm
Caenorhab. elegans
Q21929
251
27201
N42
Q
V
I
A
F
A
R
N
E
A
N
L
L
S
L
Sea Urchin
Strong. purpuratus
XP_783056
275
30198
T43
P
G
S
V
L
V
L
T
G
R
S
A
A
D
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P40579
254
27462
A35
D
T
V
V
Y
G
V
A
R
S
E
A
P
L
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.5
96.9
80.9
N.A.
74.3
74.4
N.A.
46.3
26.4
55.5
52.4
N.A.
N.A.
25.4
26
39.6
Protein Similarity:
100
98
99.6
89.1
N.A.
86.5
88.1
N.A.
58.6
44.8
69.9
74.3
N.A.
N.A.
41.5
46.3
58.5
P-Site Identity:
100
100
86.6
93.3
N.A.
53.3
73.3
N.A.
0
26.6
60
73.3
N.A.
N.A.
46.6
13.3
60
P-Site Similarity:
100
100
100
93.3
N.A.
86.6
86.6
N.A.
0
53.3
80
93.3
N.A.
N.A.
60
26.6
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
28.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
48.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
15
8
8
8
15
65
15
0
15
8
43
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
0
0
0
0
0
0
8
22
0
8
8
% D
% Glu:
0
0
8
0
0
0
0
8
8
0
8
22
50
0
0
% E
% Phe:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
72
0
8
0
8
0
0
15
0
8
0
0
0
0
% G
% His:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
8
0
0
0
0
0
0
8
0
0
0
% I
% Lys:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% K
% Leu:
0
0
0
0
65
29
65
8
0
0
0
22
8
15
86
% L
% Met:
0
8
0
0
8
0
0
0
0
0
0
0
0
15
0
% M
% Asn:
0
0
0
0
0
0
0
15
0
0
43
8
8
0
0
% N
% Pro:
65
0
0
0
0
0
0
0
0
8
0
0
8
0
0
% P
% Gln:
8
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% Q
% Arg:
15
0
0
0
0
0
15
0
8
65
0
0
0
0
0
% R
% Ser:
0
0
72
0
0
8
0
36
8
8
29
8
15
15
0
% S
% Thr:
0
8
8
8
0
0
0
15
0
8
8
0
0
0
0
% T
% Val:
0
15
8
65
0
43
15
8
0
0
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
8
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _